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Read the evidence-based publications showing why HeartTrends' Multipole Parameter Weight (MPW) analysis  is the up-and-coming test for early cardiac screening. Just click to view and download.

Heart Rate Variability for Risk Assessment of Myocardial Ischemia in Patients Without Known Coronary Artery Disease: The HRV-DETECT Study. Goldenberg I, et al.
J. Am. Heart Assoc. (2019) 8:e014540

Comparison of the Usefulness of Heart Rate Variability vs. Exercise Stress Testing for the Detection of Myocardial Ischemia in Patients Without Known Coronary Artery Disease. Goldkorn R, et al. Am. J. Cardiology (2015) 115:1518-1522

Alterations in heart rate variability are associated with abnormal myocardial perfusion. Shah A., et al. (Emory University) International J. Cardiology (2020) 305:99-105


Description of complex time series by Multipoles. Lewkowicz M, et al.
Physica Acta (2002) 311: 260-274

Statistical analysis of the Diamond MI study by the Multipole Method. Olesen RM, et al.
Physiol. Meas. (2005) 26: 591-8

Multipole Analysis of Heart Rate Variability as a Predictor of Imminent Ventricular Arrhythmias in ICD Patients. Rozen G, et al. Pacing Clin. Electrophysiol. (2013) 36:1342-7

Heart Rate Variability Density Analysis and Prediction of Long-Term Mortality after Acute Myocardial Infarction. Jorgensen et al. Ann Noninvasive Electrocardiol. (2016) 21:60–68

A Novel Heart Rate Variability Algorithm for Detection of Significant Coronary Artery Disease – Pilot Data from a Prospective Clinical Trial. Oieru D, et al. IMAJ 2015 17:161-165

Heart Rate Variability Density Analysis for Identification of Appropriate Implantable Cardioverter Defibrillator (ICD) Recipients, Jorgensen RM, et al. Europace (2015) 17:1848-58

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